Perlane®

Effective July 1, 2015, Perlane received FDA Approval for additional treatments and is now offered under the Restylane Lyft label. Click here to learn more!


Perlane® for Deep Wrinkles

California Skin Institute providers offer Perlane® filler injections as a way to add volume to the treatment site and reduce the appearance of deep wrinkles and creases, such as nasolabial folds.* This dermal filler is part of the Restylane® family of fillers, which are based on the moisture-attracting qualities of hyaluronic acid.* However, unlike Restylane® or Restylane Silk®, Perlane® is specifically designed to address deeper wrinkles, and has been effectively used by California Skin Institute providers to treat problems like nasolabial folds and laugh lines.*

perlane before after* Actual Perlane patient. Individual results may vary. Photo courtesy of Perlane.

Submit Contact Form for a Perlane Consultation

What is Perlane®?

Perlane® is an injectable gel that creates volume under the skin to smooth out deep wrinkles and facial lines.* This filler is designed specifically to target deeper wrinkles that may be more difficult to treat with other hyaluronic acid fillers.*

As such, Perlane® injections are often delivered at deeper skin levels and contain larger hyaluronic acid molecules, to create greater volume increase more efficiently.*

How Perlane® Works

The mechanism by which Perlane® filler treats wrinkles relies on the hydrophilic (water-loving) properties of hyaluronic acid.* This chemical occurs naturally in our bodies and can hold many times its weight in moisture.*

In Perlane®, this acid is delivered in concentrated form, quickly drawing moisture to the target area and providing nearly-instantaneous increases in volume under the skin.*

Further, Perlane® filler is formulated in a way that slows down the natural breakdown of hyaluronic acid to provide longer-lasting improvements, and is prepared in a way that makes it non-immunogenic (your immune system is highly unlikely to respond to the gel with inflammation).*

What Perlane® Treats

Perlane® is formulated specifically for deep lines and wrinkles that are not easily treated with other hyaluronic acid fillers.* California Skin Institute providers most commonly use Perlane® injections to treat nasolabial folds and laugh lines.*

Perlane® typically isn’t injected into the lips, as the size of the hyaluronic acid molecules and unique chemical dynamics of this filler may create a bumpy, misshapen appearance under the thin skin of the lips (something that is not a concern with the thicker skin around the mouth).* For lip enhancement injections, Restylane Silk® is typically a much better option.*

Submit Contact Form for a Perlane Consultation

How Long does Perlane® Last?

Improvements will appear shortly after the Perlane® injections are performed, and typically continue to improve over several days, as the hyaluronic acid draws more moisture to the treatment site.*

Upkeep treatments may prolong the effects of this dermal filler.*

What to Expect During Perlane® Treatment

During your visit to California Skin Institute, your provider will examine your skin to determine how much Perlane® will be needed for optimal outcomes.* Typically, more of this filler is needed for wrinkles that are very deep.*

However, it’s also important to retain a natural appearance, as too much of this filler can create an unnatural appearance when you smile.*

To create improvements that look natural, your California Skin Institute provider will administer the Perlane® filler at several injection sites, using a very thin needle.* Using several injection sites allows the wrinkles to be filled in a balanced way, and a small needle prevents significant bruising or discomfort.*

Does Perlane® Hurt?

California Skin Institute providers go to great lengths to ensure the comfort of each patient.* As such, we will use either a local anesthetic or a numbing cream to ensure that the Perlane® injections are as painless as possible.* The vast majority of patients tolerate this procedure very easily.*

To learn more about Perlane®, complete the Contact Form below, or call a California Skin Institute practice near you!

* Individual results may vary and are not guaranteed.

Schedule a Perlane® Consultation
Is there anything else you would like us to know?

*Individual results may vary and are not guaranteed.